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Together with our previous observations that the LSM domain of LSM14 interacts with both the middle and Cterminal regions of 4ET, these results suggest that both LSM14interaction motifs in 4ET function redundantly and bind to LSM14 in a similar manner

Inhibition of 25-OHC expression or treatment with Fer-1, a ferroptosis inhibitor, significantly suppressed ferroptosis and lipid peroxidation in IMS32 cells and alleviated neurological damage, indicating that 25-OHC may serve as a potential therapeutic target for ALS (Urano et al., 2025)

Ruben MD, Hogenesch JB, Smith DF

One area of ongoing investigation in hormone replacement therapy is the differential cancer risks among individuals undergoing gender-affirming hormonal therapy (GAHT) (368)Jackson SS, et al