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Azathioprine is a prodrug that is converted into 6-mercaptopurine by glutathione transferases (GST)

In one human study that showed improvements in kidney stones, the daily dosage was 4.5 grams of chanca piedra infused in one cup of hot water twice daily for 12 weeks ( Chanca piedra pills or capsules contain anywhere from 500 to 1,600 mg of the herb per dose, and liquid extracts contain a similar amount