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Mice were monitored weekly for palpable tumors, commencing at an age of 8 weeks

These concepts are vital for understanding buffer systems in living organisms

361368, Cui, J., et al

However, PAI-1 carbonylation has been demonstrated to influence its functional activity and structural stability [38], therefore carbonylated PAI-1 may exhibit reduced activity, and we hypothesize that it could trigger a compensatory mechanism leading to an increase in its overall concentration observed in our cohort