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In line with this is an important concept in the study of G protein-coupled receptors (GPCRs): the idea of receptor oligomerization, in which GPCRs interact with other GPCRs in close proximity, resulting in physical association with possible conformational changes as well as changes in intracellular signaling and/or ligand binding

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Excessive ROS production leads to detrimental effects on mitochondrial proteins and lipids, causing oxidative damage and facilitating ferroptosis ( The underlying cause of ferroptosis is a disequilibrium between the bodys oxidants and antioxidants