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(2) Reagent preparation Preparation of 9 different concentrations of modified Hams F10 medium according to orthogonal experimental design: 160 mg of L-carnitine and 5 mg fructose were fully dissolved in 20 ml Hams F10 medium, thoroughly shaken and mixed, filtered through a microwell filter, and placed in a sterile bottle for later use (the final concentrations see Table 2)

Even with a perfect taper, there's a 7-10 day window where endogenous GH output is slightly below baseline

It contributes to IR by inhibiting Akt phosphorylation (260)