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Am J Pathol

5 The nucleus: A genome-associated dynamic network for precision targeted strategies 5.1 Structure of nucleus The nucleus, the living hallmark of eukaryotic cells, is the housekeeper of the majority genomes, playing a crucial role in maintaining the stability of genetic materials and regulating osteogenesis and metabolism (200)

Younes A, Consoli U, Snell V, Kliche K, Thomas E, Armitage R, Cabanillas F, Andreeff M

353 In addition to the above-known pharmacological mechanisms, some recent studies have reported that amitriptyline can induce the activation of fibroblast growth factor receptor (FGFR), leading to the production of GDNF