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Although glucagon action is primarily liver specific, glucagon receptors have been reported to be present in membranes of human adipose tissue (83), suggesting that direct action of glucagon likely plays an important role in regulating human, as well as rodent, lipolysis

Blood Adv 6:5829-34 Batista KS, Cintra VM, Lucena PA, Manhes-de-Castro R, Toscano AE, Costa LP, Queiroz ME, de Andrade SM, Guzman-Quevedo O (2022) Aquino JdS: The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the musclegutbrain axis and implications for SARS-CoV-2 infection

conversely, myxoedematous (hypothyroid) cretinism, the less prevalent form, exhibits attenuated cognitive impairment, growth retardation, thyroid hypofunction, alongside diverse somatic manifestations including dry and coarse skin texture, hoarse vocalization, and delayed pubertal development [122,123,124,125]

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