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Protein S -mycothiolation is reversible and dethiolation is catalyzed by mycoredoxin-1 (Mrx1), a Grx analog that functions exclusively in MSH-dependent electron transfer reactions [196]

It has been proposed for treatment of PD due to an in vitro study showing it prevents tunica albuginea fibroblast proliferation, attenuates TGF-B mediated deposition of collagen, reduces deposition of elastin, and increases fibrinolytic activity (31-33)