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Observation of mitochondrial ROS and of mitochondrial membrane potential Live cell imaging was performed with MitoSOX Red (Thermo Fisher Scientific) and with JC-1 (5, 5, 6, 6-tetrachloro-1, 1, 3, 3-tetraethylbenzimidazolylcarbocyanine iodide) (Thermo Fisher Scientific) to observe mitochondrial ROS and the mitochondrial membrane potential, respectively