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The identification of oxygen as the ultimate electron acceptor after the formation of disulphide bonds in proteins means that the products of the reduction of oxygen have to be removed to prevent damage to cellular components

So the amount of available acetyl-CoA acts as a feedback loop to suppress pyruvate dehydrogenase complex formation

Because of the low expression of Slc7a11, mice have insufficient ability to regulate iron homeostasis, and a high-iron diet leads to significant ferroptosis characteristics and causes severe heart injury and hypertrophic cardiomyopathy [89]

pylori ) which is the key risk factor of non-cardia gastric cancer has decreased (7)