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Activation of the Nrf2 pathway in Schwann cells can promote the recovery of nerve function by reducing OS and inflammation, which are critical components of secondary injury following sciatic nerve injury (Zhou et al., 2023)

Mitochondrial oxidation of fatty acids and glucose is the main source of energy required for the adult heart, providing more than 90% of ATP (Ussher et al., 2016

Alternatively, it is tempting to speculate that therapeutic interventions that could prevent the sequestration of apoC1 in TRLs or its structural modifications (truncation, oxidation, glycation) could improve its inhibitory function against CETP and restore, maintain or magnify its anti-atherogenic function