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518 The activation of thyroid hormone receptors subsequently stimulates mitogenesis and hepatocyte proliferation by modulating the Wnt/-catenin pathway, both in the normal liver and in the remnant liver after resection

Materials and Methods In Vivo Experiment Experimental Animals Specific pathogen-free male SpragueDawley rats (aged 56 weeks, 180200 g) were purchased from the Animal Experiment Center of Xinjiang Medical University (Urumqi, China)

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ECG were recorded after mild sedation with ketamine (50 mg/kg body weight) and xylazine (5 mg/kg body weight), using a 60 W light bulb to maintain warmth, using a lead II system with three electrodes configuration: the negative electrode was placed on the right forelimb, the positive electrode on the left hind limb, and the neutral electrode on the right hind limb