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These rogue cells then clump together to create tumors or spread throughout the body, invading normal tissues and causing severe damage or destruction

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After the lag phase, sensor recovery proceeded only slightly slower compared to the wt

The demand for Se will increase after suffering environmental pressures, and supplementation is a necessary condition to meet the needs of fish growth ( 4.1 Harmful effects of selenium excess Se is an essential micronutrient required for fish, which plays an important role in the antioxidant system and also affects the lipid metabolism, sugar metabolism and amino acid metabolism of aquatic animals ( Acipenser transmontanus ), excessive Se in the diet leads to vacuolar degeneration of cells and necrosis of the liver ( 4.2 Harmful effects of Se deficiency The necessity and demand for dietary Se have been estimated in various fish ( 5 Effects of Se-rich fish on humans Food is the main source of Se intake by the human