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15 A singlecentre study on patients with solid tumours and hematologic cancers revealed iron deficiency and anaemia in 42.6% and 33% of the subjects, respectively, with highest iron deficiency rates in pancreatic, colorectal and lung cancers

Compelling evidence has shown that oxidative stress promotes the development of other ovarian aging-related etiologies, including telomere shortening, mitochondrial dysfunction, apoptosis, and inflammation, which provides new insights into our understanding of the mechanisms of ovarian aging

GRB2, a HER2 adaptor protein, binds BECN1 to inhibit autophagy by suppressing VPS34 activity 38

This is important because while a large number of immune cells in the gut are activated by GLP-1 very few immune cells containing GLP-1 receptors are present in other organs