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For patients with T-ALL and a poor response to prednisone prophase, both DFS and OS rates were significantly better with allogeneic HSCT.[92] In a large retrospective series of patients with initial induction failure, the 10-year OS rate for patients with persistent leukemia was 32%.[41] A trend for superior outcome with allogeneic HSCT, compared with chemotherapy alone, was observed in patients with T-cell phenotype (any age) and with B-ALL who were older than 6 years

Previous studies employing chronic lead and cadmium exposure in rats or mice show significant changes in liver enzyme activity after longer timeframes 38,39

Sarkar S, Perlstein EO, Imarisio S, et al

Environ Toxicol 28:479488 Lamm DL, Riggs DR (2000) The potential application of Allium sativum (garlic) for the treatment of bladder cancer