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BloodCSF barrier breakdown was the most frequent pathological finding in a multicenter study of 127 patients with COVID-19 with neurological impairment 66

We covered the origins of myofibroblasts as well as the roles of TGF- in facilitating fibroblast transformation to myofibroblast, epigenetic regulators of fibrotic gene expression, ECM proteins, the fibrotic microenvironment, and the regulation of the immune system