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While sweating has many benefits, such as being a "natural function that the body uses to regulate body temperature," explains Jewel Kling, MD, assistant director of women's health for Mayo Clinic, it can also be a source of concern

The diversity of extracellular vesicles (EVs) (338, 339) and the minimal uniformity regarding the methodologies for their isolation, purification, and characterization (340) make the application of EVs in the clinical setting challenging

The BRONCUS (Bronchitis Randomized On NAC Cost Utility Study) study indicated the possible benefit of the approved standard dose of NAC (600 mg/day) in reducing exacerbations in patients with moderate-to-severe COPD, but this effect may be limited to patients not treated with ICS [99]

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