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Decreased GSH and accumulated ROS levels lead to lipid peroxidation and ferroptosis-mediated tumor suppression

The biochemical mechanism of the Wolff-Chaikoff effect has not been fully elucidated, but it is partially mediated by the downregulation of the sodium-iodide symporter (NIS) (276)

Enzymatic antioxidants are superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx), and nonenzymatic antioxidants are vitamin E, vitamin C, vitamin A, selenium (Se), transferrin, and lactoferrin

Li Y, Cao Y, Wang J, Fu S, Cheng J, Ma L, Zhang Q, Guo W, Kan X, Liu J (2020) Kp-10 promotes bovine mammary epithelial cell proliferation by activating GPR54 and its downstream signaling pathways