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Description

GLUT1 inhibitors, including STF-31, GLUTOR, and BAY-876, 939 have shown promising anticancer effects by reducing glucose uptake in cancer cells, subsequently suppressing tumor growth

The increased hepatic IDO1, plasma KYN level, plasma cholesterol level and reduced SR-BI expression in OVX animals further suggest an inverse correlation between hepatic IDO1 and SR-BI expression and their potential impacts in regulation of plasma cholesterol and lipid levels