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They stated: "The new system describes 4 basic stages of heart disease and failure : " Stage A identifies patients at high risk for developing heart disease but that currently have no identifiable structural disorder of the heart (e.g., every Cavalier King Charles Spaniel without a heart murmur)." (So, Stage A means the dog does not have any MVD murmur but that its breed is at high risk for developing MVD.) " Stage B identifies patients with structural heart disease (e.g., the typical murmur of mitral valve regurgitation is present), but that have never developed clinical signs caused by heart failure

The FA composition has been visualized in Fig

These compounds influence a wide range of physiological processes in the host, including gut barrier function, immune regulation, and nutrient absorption (90)

Trotti LM, Becker LA