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Research demonstrates that BPC-157 upregulates VEGFR2 at both mRNA and protein levels in vascular endothelial cells without increasing VEGF-A itself, effectively sensitizing cells to existing VEGF in the tissue microenvironment rather than simply adding more growth factor signal

Autophagy 8:903914 Martina JA, Diab HI, Brady OA, Puertollano R (2016) TFEB and TFE3 are novel components of the integrated stress response