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ROS activity in the vessel wall contributes to the formation of oxidized LDL, a major contributor to the pathogenesis of atherosclerosis (205, 206)

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We note that Premia Spine, Inc submitted an application for new technology add-on payments for the TOPS TM System for FY 2023, as summarized in the FY 2023 IPPS/LTCH PPS proposed rule (87 FR 28346), that it withdrew prior to the issuance of the FY 2023 IPPS/LTCH PPS final rule (87 FR 48960)