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[PMC free article: PMC2991104] [PubMed: 21035758] 179

The risk calculus is straightforward

While TXG reduces inflammation by reducing TNF- and increasing anti-inflammatory IL-10, it reduces OS by lowering levels of MDA, superoxide anion production, and the expression of iNOS, NOX, COX-2, and p47 (125) ( Supplementary Table 1 )