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After injection, the most common side-effects were pain or injection-site reactions (all of mild intensity)

Y.WangX.et al

But if toxic impairment has not been tested for and corrected, other therapies such as counseling may not be effective until eliminating the toxic burden

This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation