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10.1038/ncomms14844 Nat

The same vial stored at room temperature degrades to 8C for extended periods) often show measurable GSH loss before visible color change occurs

Now a 500mcg dose requires only 0.05mL (5 units), and the vial yields 20 administrations at that dose

These findings have stimulated clinical development attempts, particularly for NAD + modulators deemed suitable for human trials in terms of safety and upscaling, such as natural precursors