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Immune-related pathologic response criteria (irPRC) is a standardized, universal scoring system for assessing pathologic response to immunotherapy, inclusive of immune-mediated tumor regression ( In our study, all patients received scheduled surgery within 29-42 days of initiating imiquimod therapy, demonstrating the feasibility of neoadjuvant imiquimod therapy without delay in surgery

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10.3390/nu13072440 76 LeeY

Alongside oestrogen imbalance linked to methylation challenges, we often see low glutathione, increased oxidative stress, and inflammation driving pigmentation