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A study investigated the relationship between hepatic diseases and psychiatric symptoms, focusing on the prevalence and impact of mental health disorders in hospitalized cirrhosis patients in the United States from 2002 to 2014 and found that 37% of cirrhosis patients had a mental illness diagnosis, with prevalence rising from 22.6% in 2002 to 54.1% in 2014

In humans, increased plasma concentrations have not been conclusively associated with an increase in the skeletal muscle carnitine pool [23]

Nat Rev Drug Discovery

These findings suggest that the immune system misidentifies self-antigens, which in turn drives the production of pathogenic autoantibodies [30]