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Zarka, M.H., & Bridge, W.J

FIGURE 4 Effect of GA on Isoproterenol-Induced Inflammatory Marker Expression in Heart Tissue The expression of TNF-, IL-6, NF-B, COX-2, and iNOS was significantly upregulated in ISO-treated rats (Group III)

Once inside the cell, Fe 3+ is reduced to Fe 2+ via six-transmembrane epithelial antigen of prostate 3 (STEAP3) and transported into the cytosol by divalent metal transporter 1 (DMT1) and ZRT/IRT-like proteins 8 and 14 (ZIP8/14) (Wang et al., 2025d)