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One posited mechanism is the activation of phospholipase C (PLC), which, according to some researchers, might subsequently facilitate the release of inositol triphosphate (IP3) and diacylglycerol (DAG)

Angiogenesis Seiwerth et al

The main mechanism of action is based on the combination of the anorectic effect of GLP-1, the lipolytic and thermogenic characteristics of glucagon, and the action of GIP on -cell function and glycemic control

Since the low concentrations of cobalamin in our subjects were found as part of a screening program, in the absence of specific clinical symptoms, we assume that the subjects were at an early stage of negative cobalamin balance [16]