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EAAC1 is expressed in retinal neurons including RGCs, while GLAST is mainly expressed in Mller glial cells

10.1002/med.21507 73 ZhangL.ChengQ.ZhangL.WangY.MerrillG

Excitation of Az488/Alk488 and AzCy5/AlkCy5 were achieved with 488 and 642 nm laser excitations, respectively

Regulatory bodies such as the FDA and EMA have implemented rigorous guidelines to address the specific challenges encountered with pulmonary nanotherapeutics, ensuring comprehensive preclinical evaluations including pharmacokinetics, biodistribution, and toxicity studies, with particular attention to lung-specific endpoints like alveolar inflammation and mucociliary clearance ( 2+ release (Sun et al., 2023)