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Additionally, hiPSCs, derived from patients can be utilised to interrogate disease mechanisms and provide a potential source of autologous cells for regenerative medicine 13

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1c, Supplementary Data 1 and Supplementary Table 4), together with processes linked to neuronal development, synaptic and dendritic organization, known to be modulated by oligodendroglial-dependent brain plasticity and adaptive myelination 41,42,43,44

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