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The results showed that the Ace-tubulin/Try-tubulin ratio in the vitamin B12+4-PBA group was increased relative to the vitamin B12 group, which was consistent with MAP-2 in mice (Figure 4O,P)

Push the plunger back to the desired dosage to draw air into the syringe

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Once that is completed, small trials will commence on volunteers. Once stage 2 trials show safety and benefit, they can proceed to larger phase 3 trials to again analyze data across a large population, he added