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Role of BDNF/mTORC1 signaling in the long-lasting antidepressant effects of (2R,6R)-hydroxynorketamine

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have reported that low levels of frataxin leads to the reduced expression of NRF2 and antioxidants present in the dorsal root ganglia of FRDA mouse models (Shan et al., 2013)

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The expression and activities of GPX3 are changed in many pathological processes involved in systemic non-neoplastic disorders, such as kidney diseases, cardiovascular diseases, respiratory diseases, metabolic diseases, digestive system diseases, neurological disorders, bone and joint diseases, and other diseases (Figure 3)