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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

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For context on how this compares to other peptide administration schedules, the fat loss peptide overview covers dosing frequency across multiple compounds

This can occur in early coeliac disease or other conditions (infection, autoimmune disease, IBS)