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Nature 513, 5964

doi: 10.1016/j.bbamem.2016.02.002 Deplazes, Evelyne, Davies, Josephine, Bonvin, Alexandre M

As such, a mechanism to sense and respond to amino acid depletion may be crucial for T cell anti-tumor response in solid tumors

Dopaminergic neurons are particularly vulnerable due to decreased antioxidant concentration with aging, constant exposure to ROS and presence of neurotoxic compounds (e.g