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Reducing the over/misprescription of antibiotics requires twofold action behavioral change in healthcare providers and patients using stewardship programs and better, rapid tests that can discriminate bacterial and viral infections [275]

The latter possibility, however, appears unlikely, since in line with the assumption that the thiol oxidation is catalyzed by the enzyme-bound Cu 2+ , CSH (similarly to other thiols) was incapable of extracting metal ions (Cu 2+ or Zn 2+ ) from the active site of holo-SOD1 WT (Fig

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doi: 10.1124/dmd.108.020503 202 SeidenstickerMFabritiusMPBellerJSeidenstickerRTodicaAIlhanHet al