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doi: 10.1016/j.jaut.2018.05.008 176 TremellenKPearceK

Optical properties of platelets and blood plasma and their inuence on the optical behavior of whole blood in the visible to near infrared wavelength range

HCQ and CQ exert their immunomodulatory effects by inhibiting TLR7 and TLR9 signaling, which plays a crucial role in the pathogenesis of autoimmune diseases such as SLE (101103)

Due to the lack of side chain densities, we cannot accurately model side chain conformations for most of residues in this loop, except for Y31 whose side chain is clearly resolved in the cryo-EM map (Supplementary Fig