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Lewis S, Chen L, Raghuram V, Khundmiri SJ, Chou CL, Yang CR, et al

Clinical pharmacokinetics of ondansetron and 8-hydroxyondansetron after repeated intravenous and oral administration in healthy volunteers

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258 Reduced glucose metabolism often precedes clinical AD symptoms, initially affecting the parietal-temporal lobes and posterior cingulate cortex before spreading to other regions, such as the frontal lobes