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It modulates the levels of ferroptosis-related signaling pathways, including ACSL4, SLC7A11, GPX4, and FTH1, and reduces the expression of MMP3 and MMP13, which could be one of the important mechanisms and pathways underlying its inhibitory effect on RA bone destruction

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Cancer Immunol Res 10(2):228244 Cheng K, Cai N, Zhu J, Yang X, Liang H, Zhang W (2022) Tumor-associated macrophages in liver cancer: from mechanisms to therapy