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While ROS generation is modest during the ischemic phase due to oxygen deprivation (Sen et al., 2024), a substantial and rapid burst occurs upon the sudden reintroduction of oxygen during reperfusion (Xiang et al., 2021

However, over longer periods , the changes can be significant think losing fat while gaining or preserving muscle , leading to a leaner, stronger physique

Cell 2005 , 120 , 483495

Recent studies have demonstrated the utility of supervised ML algorithms in predicting key disease outcomes including progression from simple steatosis to MASH, development of significant fibrosis, and even HCC