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In the context of renal homeostasis, Bregs help to reduce tissue injury by suppressing autoimmune reactions via programmed death-ligand 1 (PD-L1) signaling and by enhancing immune complex clearance through Fc gamma receptor IIb (FcRIIb) receptors (80)

The primary research applications include: Researchers at academic institutions, pharmaceutical companies, and independent laboratories worldwide use BPC-157 for in-vitro studies, cell culture experiments, and animal model research