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This activation involves the upregulation of cell adhesion molecules (CAMs) such as selectins, ICAM-1, and VCAM-1, which facilitates the targeted recruitment and extravasation of circulating immune cells, including neutrophils, monocytes/macrophages, and lymphocytes

Brain Behav Immun 25:13841392 Ericsson A, Arias C, Sawchenko PE (1997) Evidence for an in- tramedullary prostaglandin-dependent mechanism in the activation of stress-related neuroendocrine circuitry by intravenous interleukin-1

doi: 10.3389/fchem.2024.1470458 Received 25 July 2024 Accepted 09 September 2024 Published 07 October 2024 Volume 12 - 2024 Edited by Yusuke Kato, National Agriculture and Food Research Organization, Japan Reviewed by Shinya Kato, Mie University, Japan Huaqing Cui, Chinese Academy of Medical Sciences and Peking Union Medical College, China Updates Copyright 2024 Krishnamurthy, Pereira, Rajavelu, Jayaraman, Krishna, Wang, Bei and Rajasekaran

Instead, when Pauling won his second Nobel in 1963a peace prize for his work toward nuclear disarmament and a testing banthe reaction on campus was noticeably muted