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Chen in 2013 and refined in 2023, to systematically elaborate the adaptive resistance mechanisms in cancer immunotherapy, including impaired antigen presentation, remodeling of the immunosuppressive TME, and upregulation of inhibitory ligands and receptors, among others

Oladeji, L

Senescence is triggered by internal as well as external stimulation, playing a pivotal role in organismal growth and post-injury repair

57,58 Accumulated DNA damage and cellular senescence are thought to be a common underlying mechanism linking infertility, cancer, cardiovascular disease, and other chronic diseases