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It's not a simple question, and the answer is far more nuanced than a single spot on a diagram

They are associated with oxidative stress, even though the causes differ

References AbdElrahman SH, Saudy HS, Abd ElFattah DA, Hashem FA (2022) Effect of irrigation water and organic fertilizer on reducing nitrate accumulation and boosting lettuce productivity

A minimal amount of EGT was still found in the Egt2 deletion strain, explained by a spontaneous conversion of hercynylcysteine sulphoxide to EGT by an unrelated PLP-binding enzyme 17