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A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcoma

Unlike oral supplements that must pass through the digestive system, IV therapy provides immediate absorption, ensuring faster and more noticeable results

Once inside the cell, cisplatin undergoes monoaquation, where one of the chloride ligands is replaced by a water molecule due to the lower chloride concentration in the cytoplasm (420 mM) compared to the blood (approximately 100 mM) [2,28]