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Sonic Hedgehog Promotes Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Rho/ROCK Signaling

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Histopathological examination To obtain paraffin-embedded tissue sections, formalin-fixed lung tissue specimens were drained using escalating grades of ethanol, cleansed with xylene, impregnated in paraffin wax, and sectioned at 4.5 m

A priori sample size and power calculations based on previous results from similar experiments 72,73 were performed to detect a minimum 3-fold increase of mean axon counts, a 50% increase in mean normalized CMAP amplitude, and a 50% reduction in mean normalized CMAP latency in the MSC-treated rats at the familywise error rate of 5% and 80% power