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Thus, reduced GSH levels may be common during the acute phase of Plasmodium infection, regardless of disease severity or whether the infection is caused by P

Pediatric AIH is typically characterized by hypergammaglobulinemia (raised IgG levels), indicating ongoing histological activity, although up to 15% of children with AIH-1 and 25% of AIH-2 may have normal IgG levels, particularly in acute fulminant presentations [9, 29, 43]

Future research will likely focus on elucidating the molecular mechanisms underlying astrocyte-mediated modulation of neuronal activity, the role of lactate as a signaling molecule, and how these processes are altered in neurodegenerative diseases