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Integrated supplementary information Supplementary Figure 1 GSH titration by spectrophotometer Spectrophotometer is set at 412 nm wavelength and a continuous reading is performed for a few minutes, until a plateau is reached

Recent work in Arabidopsis suggests that GCL and GS are each encoded by a single gene with alternate transcription start sites leading to either plastid-targeted or cytosolic protein (Wachter et al., 2005)

Glutathione contains a high amount of cysteine, which is a sulfur-containing amino acid

Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in saccharomyces cerevisiae