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Effects of vitamin B12 on performance and circadian rhythm in healthy subjects

Nrf2-deficient mice exposed to CS had more extensive emphysema and more pronounced airway inflammation than wild-type mice

IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes