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HIV envelope protein gp120 and the regulatory virus protein, Tat, are involved in BBB breakdown

A 10-YEAR COHORT STUDY Georgia Sofia Karachaliou 1 Amy Perkins 2 Chad Dorn 2 Qingyi Wei 3 Xiaoming Xu 4 Sheng Luo 4 Glenn Gobbel 2 Ruth Reeves 2 Mustafa Bashir 5 Manal Abdelmalek 6 Anna Mae Diehl 5 Ayako Suzuki 3 , 1 Duke University Medical Center, 2 Veterans Administration Medical Center, Nashville, TN, 3 Department of Medicine, Duke University Medical Center, Durham NC, 4 Department of Biostatistics and Bioinformatics, Duke University, Durham NC, 5 Duke University, 6 Mayo Clinic Rochester Background: Statins are associated with reduced risks of cirrhosis and hepatocellular carcinoma in patients with NAFLD